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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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1 – 15 of 119 results
1

MilliporeSigma™ Proteinase K, Lyophilized

Highly active serine protease that exhibits broad cleavage specificity on native and denatured proteins and is widely used in the purification of DNA and RNA

Content And Storage 2°C to 8°C
CAS 39450-01-6
Product Type Proteinase K
2

Thermo Scientific Chemicals Papain, Carica Papaya Latex

CAS: 9001-73-4 Synonym: EC 3.4.22.2

CAS 9001-73-4
Synonym EC 3.4.22.2
3

Thermo Scientific™ Pierce™ Immobilized TCEP Disulfide Reducing Gel

Efficiently reduce protein or peptide disulfide bonds with this stable, odorless, beaded agarose resin on which Tris (2-carboxyethyl) phosphine is immobilized.

4

Thermo Scientific™ Bond-Breaker™ TCEP Solution, Neutral pH

Efficiently reduce protein disulfide bonds with this stable, odorless, 0.5M solution of TCEP reducing agent that is ideal for making reducing SDS-PAGE sample buffers.

5

Thermo Scientific™ Pierce™ Alkylating Reagents

Alkylating reagents provided in single-use, pre-weighed formats to streamline protein preparation workflows.

Product Type Alkylating Reagent
Product Line Pierce™
6

Thermo Scientific™ DTNB (Ellman's Reagent) (5,5-dithio-bis-(2-nitrobenzoic acid)

Measure peptide cysteines or other free, reduced sulfhydryls (-SH groups) in solution using this thiol-reactive, colored compound (Amax 412nm).

10

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, Molecular Biology Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 3483-12-3
Product Type Calbiochem Cleland’s Reagent
Form Crystalline Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym 1,4-Dithiothreitol, DTT
Molecular Formula C4H10O2S2
11

MilliporeSigma™ Calbiochem™ Coenzyme A, Trilithium Salt

Serves as cofactor in enzymatic acetyl transfer reactions

12

MilliporeSigma™ Calbiochem™ Carboxypeptidase B, Porcine Pancreas

Native carboxypeptidase B catalyzes the release of C-terminal from basic amino acids, arginine, lysine, or ornithine from polypeptides

13

MilliporeSigma™ Calbiochem™ BAPTA/AM

Can be loaded into wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA

Membrane Permeable Y
Content And Storage -20°C
CAS 126150-97-8
Product Type Calbiochem BAPTA/AM
Form Solid
Solubility DMSO
Purity ≥90% by TLC
Synonym 1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester
14

MilliporeSigma™ Chymotrypsin, Human Pancreas

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV

15

MilliporeSigma™ Calbiochem™ Cleland’s Reagent, ULTROL™ Grade

Protective agent for SH groups

Content And Storage 2°C to 8°C
CAS 3483-12-3
Product Type Calbiochem Cleland’s Reagent
Form Solid
Molecular Weight (g/mol) 154.24
Solubility EtOH, Water
Purity ≥99% by titration
Synonym Dithiothreitol, DTT
Molecular Formula C4H10O2S2