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Naloxone hydrochloride, 98%
Naloxone hydrochloride, CAS # 357-08-4, is involved in the blockade of the mu-opioid receptor and removal of other compounds from the receptor site. | CAS: 357-08-4 | C19H22ClNO4 | 363.838 g/mol
Supplier: Thermo Scientific Chemicals J6001303
Description
A specific opiate antagonist. Blocks the action of sigma-agonists at opioid sites.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone
Application
- Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds
Specifications
| Naloxone hydrochloride | |
| 200°C to 205°C | |
| C19H22ClNO4 | |
| 1 g | |
| naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride | |
| RGPDIGOSVORSAK-STHHAXOLSA-N | |
| (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | |
| 5464092 | |
| 98% |
| 357-08-4 | |
| White | |
| MFCD00069322 | |
| 14,6362 | |
| Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether | |
| C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl | |
| 363.838 | |
| 363.84 | |
| Crystalline Powder |
Chemical Identifiers
| 357-08-4 | |
| 363.838 | |
| RGPDIGOSVORSAK-STHHAXOLSA-N | |
| 5464092 | |
| C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl |
| C19H22ClNO4 | |
| MFCD00069322 | |
| naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride | |
| (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 206-611-0
RTECSNumber : QD2275000
TSCA : No
storageNote1 : 2° to 8°C
Recommended Storage : Keep cold
RUO – Research Use Only