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Naloxone hydrochloride, 98%

Naloxone hydrochloride, CAS # 357-08-4, is involved in the blockade of the mu-opioid receptor and removal of other compounds from the receptor site. | CAS: 357-08-4 | C19H22ClNO4 | 363.838 g/mol

$1054.11 - $1054.11

Chemical Identifiers

CAS 357-08-4
Molecular Formula C19H22ClNO4
Molecular Weight (g/mol) 363.838
MDL Number MFCD00069322
InChI Key RGPDIGOSVORSAK-STHHAXOLSA-N
Synonym naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
PubChem CID 5464092
IUPAC Name (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
SMILES C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6001303
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Thermo Scientific Chemicals
J6001303
1 g
Each for $1,054.11
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Description

Description

A specific opiate antagonist. Blocks the action of sigma-agonists at opioid sites.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone

Application

  • Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds
Specifications

Chemical Identifiers

357-08-4
363.838
RGPDIGOSVORSAK-STHHAXOLSA-N
5464092
C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
C19H22ClNO4
MFCD00069322
naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride

Specifications

357-08-4
White
MFCD00069322
14,6362
Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether
C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
363.838
363.84
Crystalline Powder
200°C to 205°C
C19H22ClNO4
1 g
naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
RGPDIGOSVORSAK-STHHAXOLSA-N
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
5464092
98%
Naloxone hydrochloride
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

EINECSNumber : 206-611-0

RTECSNumber : QD2275000

TSCA : No

storageNote1 : 2° to 8°C

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only