MilliporeSigma™ Supelco™ CHIRALPAK™ CBH HPLC Guard Column, 5 μm Particle Size

Description

CHIRALPAK™ CBH phase has cellobiohydrolase as the chiral selector immobilized on spherical 5 μm silica particles. Used in reversed-phase mode, retention and enantioselectivity is regulated by changes of pH, buffer concentration and organic modifier. The mobile phases are mixtures of phosphate or acetate buffers and organic solvents such as 2-propanol or acetonitrile. The column is preferably used for the separation of enantiomers of basic drugs, particularly compounds containing one or more nitrogen atoms along with one or more hydrogen-bonding groups (alcohol, phenol, carbonyl, amide, ether, ester, etc.). Features: Direct reversed phase resolution of chiral molecules. Stable with a variety of organic modifiers. Available in analytical and semi-preparative sizes.