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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (3,913)
HPLC Guard Columns and Cartridges (549)
HPLC Guard Column Accessories (33)

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1 – 15 of 1,277 results
1

Thermo Scientific™ HyPURITY™ C18 HPLC Columns, 3μm Particle Size

Thermo ScientificTM HyPURITYTM C18 HPLC Columns are available in limited dimensions. Please contact Customer Service for more details.

2

Thermo Scientific™ Hypercarb™ Porous Graphitic Carbon HPLC Columns

Use for enhanced retention of polar compounds and separation of structurally related analytes with stability at pH extremes and high temperature.

3

Thermo Scientific™ HyPURITY™ C18 Columns, 5μm Particle Size

High quality, highly pure silica columns

Pore Size 190 Å
Particle Size 5 μm
Carbon Load 13%
Stationary Phase C18
Phase Reversed Phase
Endcapped Yes
Packing Material Silica
Column Type Reversed Phase
pH 1 to 9
Surface Area 200 m²/g
USP Type L1
5

Thermo Scientific™ Accucore™ Polar Premium HPLC Columns

Use this specially designed solid core column for fast high resolution with high pH stability for separation of basic, neutral, and acidic species.

Pore Size 150 Å
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 90 m²/g
Max. Pressure 14500 psi (1000 bar)
Particle Size 2.6 μm
Carbon Load 9%
Packing Material Spherical, Solid Core, Ultrapure Silica
pH 1.5 to 10.5
Particle Shape Spherical Solid-core
Product Line Accucore
USP Type L60
6

Thermo Scientific™ Hypercarb™ HPLC Column, 5μm

Thermo Scientific™ Hypercarb™ Columns give you 100% porous graphitic carbon for extended separation capabilities

Pore Size 250 Å
Particle Size 5 μm
Carbon Load 100%
Phase Normal and Reversed Phase
Column Type Mixed Mode
pH 1 to 14
Surface Area 120 m²/g
USP Type L109
Column Format Analytical Column
8

Thermo Scientific™ Acclaim™ Trinity P2 HPLC Columns

Use these mixed-mode columns for separation of multivalent cations or anions and pharmaceuticals.

Pore Size 300 Å
Solvents Compatible with most common HPLC organic solvents except for alcohols
Stationary Phase Spherical, Nanopolymer Hybrid Silica
Temperature 45°C
Phase HILIC and Ion Exchange
Endcapped Proprietary
Column Type Mixed Mode
Green Features Responsibly packaged
Surface Area 100 m²/g
Max. Pressure 6000 psi (415 bar)
Particle Size 3 μm
Mobile Phase Compatibility 0 to 100% aqueous mobile phase
pH 2.5 to 7
Particle Shape Spherical silica
Product Line Acclaim
9

Thermo Scientific™ Hypersil™ Phenyl Drop-in Guard Cartridges

Offer convenience, economy and effective protection for extending column lifetime

10

Thermo Scientific™ Accucore™ XL C8 HPLC Columns

Improve laboratory productivity using Thermo Scientific™ Accucore™ XL C8 Columns.

Pore Size 80 Å
Particle Size 4 μm
Carbon Load 4%
Stationary Phase C8
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 9
Surface Area 130 m²/g
Max. Pressure 8700 psi (600 bar)
USP Type L7
11

Thermo Scientific™ ProPac™ Elite WCX HPLC Column

This column provides consistent separations of therapeutic proteins including monoclonal antibodies, antibody drug conjugates, biosimilars and charge variants.

Pore Size Nonporous
Stationary Phase Carboxylate
Temperature 10°C to 60°C
Phase Ion Exchange
Column Type Ion Exchange
Green Features Responsibly packaged
Max. Pressure 4500 psi (310 bar)
Column Format Analytical Column
Particle Size 5 μm
Packing Material Nonporous DVB Particles with Hydrophilic Coating
Mobile Phase Compatibility Recommended: Goods Buffers and NaCl. Minimum 20 mM salt required. Do not rinse with pure DI H2O
pH 2 to 12
Technique Bio-LC
Product Line ProPac
12

Thermo Scientific™ Hypersil™ PREP HS C18 HPLC Columns

Maximize retention and loading with Hypersil PREP HS C18 prep LC reversed phase columns which offers high loading capacity and suitable for USP-L1 Applications.

Pore Size 100 Å
Carbon Load 15%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Reversed Phase
pH 2 to 9
Surface Area 350 m²/g
USP Type L1
13

Thermo Scientific™ Accucore™ Biphenyl Reversed Phase HPLC Columns

Use this solid core column for fast and reliable separation of critical pairs and isomers.

Pore Size 80 Å
Stationary Phase Biphenyl
Temperature 70°C
Phase Reversed Phase
For Use With HPLC/UHPLC Instrumentation
Endcapped Yes
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 8700 psi (600 bar)
Particle Size 2.6 μm
Flow Rate 0.4 mL/min
Carbon Load 6%
Packing Material Spherical, Solid Core, Ultrapure Silica
Diameter (Metric) 2.1 mm
pH 2 to 8
Particle Shape Spherical Solid Core
Product Line Accucore
USP Type L11
14

Thermo Scientific™ Hypersil™ PREP BDS Phenyl HPLC Columns

Achieve unique selectivity for aromatic and slightly polar compounds with a base-deactivated Hypersil PREP Phenyl BDS prep LC column, suitable for USP L11 applications.

Pore Size 145 Å
Particle Size 5 μm
Carbon Load 5%
Stationary Phase Phenyl (Ph)
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous, Base-Deactivated Silica
Column Type Reversed Phase
pH 2 to 8
Surface Area 185 m²/g
USP Type L11
15

Thermo Scientific™ Hypercarb™ HPLC Column, 7μm

Thermo Scientific™ Hypercarb™ Columns give you 100% porous graphitic carbon for extended separation capabilities

Pore Size 250 Å
Particle Size 7 μm
Carbon Load 100%
Stationary Phase Porous Graphitic Carbon
Temperature 105°C
Phase Normal and Reversed Phase
Packing Material Porous Graphitic Carbon
Column Type Mixed Mode
Surface Area 120 m²/g
USP Type L109
Column Format Analytical Column