Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
Stealth RNAi™ siRNA Reporter Controls are ideal for use in RNA interference (RNAi) experiments to help you optimize your transfection conditions in any vertebrate cell line.
The Silencer™ Select Human Epigenetics siRNA Library contains 1563 Ambion™ Silencer Select highly potent, chemically-modified siRNAs targeting 521 epigenetic enzymes, including those mediating epigenetic signaling through the acetylation and methylation of histones.
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
The Silencer™ Select Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.
Ion channels are key components in a multitude of biological processes, including rapid changes in muscle cell contractions, epithelial transport of nutrients and ions, T cell activation and pancreatic beta-cell insulin release.