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Trimethylacetyl chloride, 98+%

CAS: 3282-30-2 | C5H9ClO | 120.58 g/mol

Supplier:  Thermo Scientific Chemicals A15051AP

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Catalog No. AAA15051AP


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Description

Description

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.
Specifications

Specifications

Trimethylacetyl chloride
-57°C
105°C to 106°C
Pungent
1.412
500 mL
385668
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
JVSFQJZRHXAUGT-UHFFFAOYSA-N
2,2-dimethylpropanoyl chloride
62493
≥98%
3282-30-2
0.985
8°C (46°F)
C5H9ClO
MFCD00000709
UN2438
Moisture sensitive
Miscible with acetonitrile.
CC(C)(C)C(Cl)=O
120.58
120.58

Chemical Identifiers

3282-30-2
120.58
JVSFQJZRHXAUGT-UHFFFAOYSA-N
62493
CC(C)(C)C(Cl)=O
C5H9ClO
MFCD00000709
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
2,2-dimethylpropanoyl chloride
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Safety and Handling

Safety and Handling

GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P210-P233-P234-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P390-P501c

H225-H290-H302-H314-H330

DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TRIMETHYLACETYL CHLORIDE

EINECSNumber : 221-921-6

TSCA : Yes

Recommended Storage : Ambient temperatures

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