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Thermo Scientific Chemicals Trimethoprim, 98%
Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial. | CAS: 738-70-5 | C14H18N4O3 | 290.32 g/mol
Supplier: Thermo Scientific Chemicals 455120250
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced • Trimethoprim has antibacterial and antiprotozoal properties
Applications
• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects
• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression
Specifications
| Trimethoprim | |
| 234.0°C to 236.0°C | |
| Authentic | |
| C14H18N4O3 | |
| trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim | |
| IEDVJHCEMCRBQM-UHFFFAOYSA-N | |
| 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine | |
| 5578 | |
| 290.32 |
| 738-70-5 | |
| 0.5% max. (105°C, 4 h) | |
| 97.5% min. (HPLC) | |
| 25 g | |
| Solubility in water: insoluble. | |
| COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N | |
| 290.32 | |
| CHEBI:45924 | |
| 98% |
Chemical Identifiers
| 738-70-5 | |
| 290.32 | |
| trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim | |
| CHEBI:45924 | |
| COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N |
| C14H18N4O3 | |
| IEDVJHCEMCRBQM-UHFFFAOYSA-N | |
| 5578 | |
| 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine |
Safety and Handling
GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
GHS P Statement
IF ON SKIN: Wash with plenty of soap and water.
If eye irritation persists: Get medical advice/attention.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER
GHS Signal Word: Warning
EINECSNumber : 212-006-2
RUO – Research Use Only