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Trichloroacetonitrile, 98%
CAS: 545-06-2 | C2Cl3N | 144.379 g/mol
Supplier: Thermo Scientific Chemicals A1056518
Description
Trichloroacetonitrile is involved as a reagent in Overman rearrangement, which is used to prepare alylic amines from allylic alcohols. It is also used to prepare bistrichloroacetimidates from diols leading to dihyrooxazines through acid catalyzed cyclization. Further, it is utilized in the synthesis of trichloroacetimidates by 1,8-Diazobicyclo[5.4.0]undec-7-ene (DBU) catalyzed addition of allylic alcohols. It finds application in the study of the methoxy methyl (MOM) catalyzed aza-Claisen rearrangement.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrichloroacetonitrile is involved as a reagent in Overman rearrangement, which is used to prepare alylic amines from allylic alcohols. It is also used to prepare bistrichloroacetimidates from diols leading to dihyrooxazines through acid catalyzed cyclization. Further, it is utilized in the synthesis of trichloroacetimidates by 1,8-Diazobicyclo[5.4.0]undec-7-ene (DBU) catalyzed addition of allylic alcohols. It finds application in the study of the methoxy methyl (MOM) catalyzed aza-Claisen rearrangement.
Solubility
Miscible with most organic solvents. Immiscible with water.
Notes
Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.
Specifications
Trichloroacetonitrile | |
-44°C | |
85°C to 86°C | |
C2Cl3N | |
Cl3CCN | |
50 g | |
605572 | |
trichloroacetonitrile, acetonitrile, trichloro, tritox, cyanotrichloromethane, trichloromethyl cyanide, trichloroethanenitrile, trichlouracetonitril, trichlor-acetonitrile, trichloromethylnitrile, nitrile trichloracetique | |
DRUIESSIVFYOMK-UHFFFAOYSA-N | |
2,2,2-trichloroacetonitrile | |
11011 | |
144.39 |
545-06-2 | |
1.44 | |
98% | |
1.441 | |
MFCD00001842 | |
UN3276 | |
14,9628 | |
Miscible with most organic solvents. Immiscible with water. | |
C(#N)C(Cl)(Cl)Cl | |
144.379 | |
CHEBI:82541 | |
98% |
Chemical Identifiers
545-06-2 | |
144.379 | |
DRUIESSIVFYOMK-UHFFFAOYSA-N | |
11011 | |
2,2,2-trichloroacetonitrile |
C2Cl3N | |
MFCD00001842 | |
trichloroacetonitrile, acetonitrile, trichloro, tritox, cyanotrichloromethane, trichloromethyl cyanide, trichloroethanenitrile, trichlouracetonitril, trichlor-acetonitrile, trichloromethylnitrile, nitrile trichloracetique | |
CHEBI:82541 | |
C(#N)C(Cl)(Cl)Cl |
Safety and Handling
GHS H Statement
H301-H311-H331
Toxic if swallowed.
Toxic in contact with skin.
Toxic if inhaled.
P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c
H301+H311+H331
DOTInformation : Hazard Class: 6.1; Packaging Group: II
EINECSNumber : 208-885-7
RTECSNumber : AM2450000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only