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Thiamphenicol
The methyl-sulfonyl analogue of chloramphenicol | CAS: 15318-45-3 | C12H15Cl2NO5S | 356.214 g/mol
$62.51 - $538.42
Chemical Identifiers
| CAS | 15318-45-3 |
|---|---|
| Molecular Formula | C12H15Cl2NO5S |
| Molecular Weight (g/mol) | 356.214 |
| MDL Number | MFCD00467983 |
| InChI Key | OTVAEFIXJLOWRX-NXEZZACHSA-N |
| Synonym | thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol |
| PubChem CID | 27200 |
| ChEBI | CHEBI:32215 |
| IUPAC Name | 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6357503
|
Thermo Scientific Chemicals
J6357503 |
1 g |
Each for $62.51
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AAJ6357506
|
Thermo Scientific Chemicals
J6357506 |
5 g |
Each for $133.27
|
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AAJ6357514
|
Thermo Scientific Chemicals
J6357514 |
25 g |
Each for $538.42
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Description
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsThiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Chemical Identifiers
| 15318-45-3 | |
| 356.214 | |
| OTVAEFIXJLOWRX-NXEZZACHSA-N | |
| 27200 | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide |
| C12H15Cl2NO5S | |
| MFCD00467983 | |
| thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol | |
| CHEBI:32215 | |
| CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O |
Specifications
| 15318-45-3 | |
| C12H15Cl2NO5S | |
| 1 g | |
| 14,9301 | |
| Soluble in acetonitrile or DMF; Slightly soluble in water | |
| CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O | |
| 356.214 | |
| CHEBI:32215 | |
| Powder |
| White to Yellow | |
| MFCD00467983 | |
| 2819542 | |
| thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol | |
| OTVAEFIXJLOWRX-NXEZZACHSA-N | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide | |
| 27200 | |
| 356.22 | |
| Thiamphenicol |
Safety and Handling
EINECSNumber : 239-355-3
RTECSNumber : AB6680000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only