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Thermo Scientific Chemicals Sulindac Sulfide
CAS: 32004-67-4 | C20H17FO2S, C20H17FO2S | 340.41 g/mol
Supplier: Thermo Scientific Chemicals J62104MC
Description
It is also shown to inhibit growth and induce apoptosis in human prostate cancer cells through a COX-1 and COX-2 independent mechanism. Sulindac sulfide is an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of cyclooxygenase-2 in human colon cancer cells, and reduces tumor burden in adenomatous polyposis patients. Human endothelial cells, HMEC-1 were treated with Sulindac sulfide and the effect on cell survival was studies by MTT assay.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
| 100 mg | |
| Active metabolite of sulindac; inhibits cyclooxygenase-1 | |
| C20H17FO2S | |
| 189°C to 191°C | |
| Signal Transduction Reagent | |
| MFCD00869764 | |
| CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1 | |
| 340.41 |
| Yellow | |
| 32004-67-4 | |
| 340.41g/mol | |
| Soluble in DMSO | |
| Powder | |
| LFWHFZJPXXOYNR-RQZCQDPDSA-N | |
| 2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid |
Chemical Identifiers
| 32004-67-4 | |
| 340.41 | |
| LFWHFZJPXXOYNR-RQZCQDPDSA-N | |
| CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1 |
| C20H17FO2S | |
| MFCD00869764 | |
| 2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid |
Safety and Handling
EINECSNumber : 250-892-2
Recommended Storage : Ambient temperatures
RUO – Research Use Only