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Rifabutin, 98%, Thermo Scientific Chemicals
Rifabutin, CAS # 72559-06-09, is a broad-spectrum antibiotic with activity against mycobacteria, gram-positive and gram-negative bacteria.
Supplier: Thermo Scientific Chemicals 461210010
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Rifabutin is a compound with antibacterial activity most commonly used against Mycobacterium tuberculosis
- Rifabutin is a derivative of Rifamycin S that acts through blocking RNA polymerase subunit beta (RpoB)
- Rifabutin is an inducer as well as a substrate of CYP3A, a cytochrome P450 enzyme
Applications
- Rifabutin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
- May be used in laboratory studies to determine drug resistance mutations present in Mycobacterium tuberculosis strains
Specifications
Rifabutin | |
97.5% min. (HPLC) | |
C46H62N4O11 | |
1 g | |
ATEBXHFBFRCZMA-VXTBVIBXSA-N | |
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1â´,â·.0âµ,³¹.0²â¶,³â°]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate | |
57448257 | |
98% |
72559-06-9 | |
Glass Bottle | |
MFCD00866816 | |
rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427 | |
CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O | |
847.02 | |
847 |
Chemical Identifiers
72559-06-9 | |
847.02 | |
ATEBXHFBFRCZMA-VXTBVIBXSA-N | |
57448257 | |
CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O |
C46H62N4O11 | |
MFCD00866816 | |
rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427 | |
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1â´,â·.0âµ,³¹.0²â¶,³â°]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate |
Safety and Handling
GHS Signal Word: Warning
RUO – Research Use Only