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Orotic acid, anhydrous, 97%
CAS: 65-86-1 | C5H4N2O4 | 156.097 g/mol
$193.29 - $511.84
Chemical Identifiers
| CAS | 65-86-1 |
|---|---|
| Molecular Formula | C5H4N2O4 |
| Molecular Weight (g/mol) | 156.097 |
| MDL Number | MFCD00006027 |
| InChI Key | PXQPEWDEAKTCGB-UHFFFAOYSA-N |
| Synonym | orotic acid, 6-carboxyuracil, orodin, oropur, orotonin, orotonsan, oroturic, orotyl, vitamin b13, whey factor |
| PubChem CID | 967 |
| ChEBI | CHEBI:16742 |
| IUPAC Name | 2,4-dioxo-1H-pyrimidine-6-carboxylic acid |
| SMILES | C1=C(NC(=O)NC1=O)C(=O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAB2534922
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Thermo Scientific Chemicals
B2534922 |
100 g |
Each for $193.29
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AAB2534936
|
Thermo Scientific Chemicals
B2534936 |
500 g |
Each for $511.84
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Description
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsOrotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Solubility
Slightly soluble in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Chemical Identifiers
| 65-86-1 | |
| 156.097 | |
| PXQPEWDEAKTCGB-UHFFFAOYSA-N | |
| 967 | |
| 2,4-dioxo-1H-pyrimidine-6-carboxylic acid |
| C5H4N2O4 | |
| MFCD00006027 | |
| orotic acid, 6-carboxyuracil, orodin, oropur, orotonin, orotonsan, oroturic, orotyl, vitamin b13, whey factor | |
| CHEBI:16742 | |
| C1=C(NC(=O)NC1=O)C(=O)O |
Specifications
| 65-86-1 | |
| C5H4N2O4 | |
| 100 g | |
| Slightly soluble in water. | |
| C1=C(NC(=O)NC1=O)C(=O)O | |
| 156.097 | |
| CHEBI:16742 | |
| 97% |
| 344°C to 347°C | |
| MFCD00006027 | |
| orotic acid, 6-carboxyuracil, orodin, oropur, orotonin, orotonsan, oroturic, orotyl, vitamin b13, whey factor | |
| PXQPEWDEAKTCGB-UHFFFAOYSA-N | |
| 2,4-dioxo-1H-pyrimidine-6-carboxylic acid | |
| 967 | |
| 156.1 | |
| Orotic acid, anhydrous |
Safety and Handling
GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 200-619-8
RTECSNumber : RM3180000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only