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Niflumic acid, 99+%
CAS: 4394-00-7 | C13H9F3N2O2 | 282.22 g/mol
Supplier: Thermo Scientific Chemicals J6048918
Description
It is used as a selective Cox-2 inhibitor and GPR35 activator. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIt is used as a selective Cox-2 inhibitor and GPR35 activator. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.
Solubility
Soluble in ethanol (∼50 mg/ml), acetone (50 mg/ml, Clear to Slightly Hazy, Yellow), methanol (∼50 mg/ml), DMSO (56 mg/ml at 25°C), and acetonitrile (∼50 mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Hygroscopic. Keep away fom strong oxidizing agents.
Specifications
| Niflumic acid | |
| 203°C to 204°C | |
| C13H9F3N2O2 | |
| 50 g | |
| Light sensitive | |
| niflumic acid, nifluril, landruma, forenol, actol, acido niflumico, nifluminic acid, acide niflumique, acidum niflumicum, acide niflumique inn-french | |
| JZFPYUNJRRFVQU-UHFFFAOYSA-N | |
| 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid | |
| 4488 | |
| 282.22 | |
| Crystalline Powder |
| 4394-00-7 | |
| Yellow | |
| MFCD00010569 | |
| UN2811 | |
| 14,6531 | |
| Soluble in ethanol (∽50mg/ml),acetone (50mg/ml,Clear to Slightly Hazy,Yellow),methanol (∽50mg/ml),DMSO (56mg/ml at 25°C),and acetonitrile (∽50mg/ml). | |
| OC(=O)C1=CC=CN=C1NC1=CC=CC(=C1)C(F)(F)F | |
| 282.22 | |
| CHEBI:34888 | |
| ≥99% |
Chemical Identifiers
| 4394-00-7 | |
| 282.22 | |
| JZFPYUNJRRFVQU-UHFFFAOYSA-N | |
| 4488 | |
| 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid |
| C13H9F3N2O2 | |
| MFCD00010569 | |
| niflumic acid, nifluril, landruma, forenol, actol, acido niflumico, nifluminic acid, acide niflumique, acidum niflumicum, acide niflumique inn-french | |
| CHEBI:34888 | |
| OC(=O)C1=CC=CN=C1NC1=CC=CC(=C1)C(F)(F)F |
Safety and Handling
GHS H Statement
H301-H312-H332-H315-H319-H335
Toxic if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302+H312+H332-H315-H319-H335
DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber : 224-516-2
RTECSNumber : QT2999100
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only