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Naloxone Hydrocloride, MP Biomedicals™

Naloxone Hydrocloride Off-white Crystalline Powder

Supplier: MP Biomedicals Inc 0219024591

Catalog No. MP219024591

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Description

The role of naloxone (1μM) and other opioids on apoptosis in several human cancer cell lines has been probed. Naloxone (10-100μM) has been used to study proliferation and neurogenesis in cultured rat adult hippocampal progenitors.
Naloxone has also been utilized to modulate the NMDA receptor activation capability of theμ-opioid receptor agonist DAMGO. It displaces morphine and other opiate agonists from the opiate receptor.
It is more potent than Nalorphine and is also an effective antagonist for mixed agonist-antagonist drugs such as pentazorcine. Naloxone has no respiratory depressant activity.

Specifications

CAS	357-08-4
Color	Off-white
Quantity	1 g
Synonym	Narcan, EN-1530, (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride, 17-allyl-4,5α- epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
InChI Key	RGPDIGOSVORSAK-STHHAXOLSA-N
Physical Form	Crystalline Powder

Melting Point	129.0°C to 129.2°C (literature)
Molecular Formula	C19H22ClNO4
Beilstein	6260807
Solubility Information	Soluble in water (50mg/mL - clear, colorless to faint yellow solution), ethanol (3.3mg/mL), or methanol (50mg/mL - clear, colorless solution).
Molecular Weight (g/mol)	363.84

Chemical Identifiers

CAS	357-08-4
Molecular Weight (g/mol)	363.84
Synonym	Narcan, EN-1530, (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride, 17-allyl-4,5α- epoxy-3,14-dihydroxymorphinan-6-one hydrochloride

Molecular Formula	C19H22ClNO4
InChI Key	RGPDIGOSVORSAK-STHHAXOLSA-N

Product Suggestions Safety and Handling

RTECSNumber : QD2275000

storageNote1 : Store at +4°C, Store Desiccated.