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N-Ethylmaleimide, 99+%
CAS: 128-53-0 | C6H7NO2 | 125.127 g/mol
$59.59 - $372.25
Chemical Identifiers
| CAS | 128-53-0 |
|---|---|
| Molecular Formula | C6H7NO2 |
| Molecular Weight (g/mol) | 125.127 |
| MDL Number | MFCD00005509 |
| InChI Key | HDFGOPSGAURCEO-UHFFFAOYSA-N |
| Synonym | n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide |
| PubChem CID | 4362 |
| ChEBI | CHEBI:44485 |
| IUPAC Name | 1-ethylpyrrole-2,5-dione |
| SMILES | CCN1C(=O)C=CC1=O |
Description
N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+ dependent internucleosomal DNA fragmentation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical Identifiers
| 128-53-0 | |
| 125.127 | |
| HDFGOPSGAURCEO-UHFFFAOYSA-N | |
| 4362 | |
| 1-ethylpyrrole-2,5-dione |
| C6H7NO2 | |
| MFCD00005509 | |
| n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide | |
| CHEBI:44485 | |
| CCN1C(=O)C=CC1=O |
Specifications
| 128-53-0 | |
| 209°C to 211°C | |
| >99+% | |
| MFCD00005509 | |
| 112448 | |
| n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide | |
| HDFGOPSGAURCEO-UHFFFAOYSA-N | |
| 1-ethylpyrrole-2,5-dione | |
| 4362 | |
| 125.13 | |
| N-Ethylmaleimide |
| 43°C to 46°C | |
| 73°C (163°F) | |
| C6H7NO2 | |
| 1 g | |
| Light sensitive | |
| Soluble in ethanol,water,chloroform,methanol and toluene. | |
| CCN1C(=O)C=CC1=O | |
| 125.127 | |
| CHEBI:44485 | |
| Crystalline |
Safety and Handling
P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
H300-H311-H314-H317-H335
DOTInformation : Hazard Class: 6.1; Packaging Group: II
EINECSNumber : 204-892-4
RTECSNumber : UX9625000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only