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Lincomycin hydrochloride
Lincomycin hydrochloride, CAS # 859-18-7, is a compound showing antibacterial activity against a wide variety of bacteria, including Staphylococcal, Streptococcal, and Bacteroides fragilis infections. It also shows inhibitory activity against protein synthesis. | CAS: 859-18-7 | C18H35ClN2O6S | 442.996 g/mol
$105.59 - $1474.67
Chemical Identifiers
| CAS | 859-18-7 |
|---|---|
| Molecular Formula | C18H35ClN2O6S |
| Molecular Weight (g/mol) | 442.996 |
| MDL Number | MFCD00058237 |
| InChI Key | POUMFISTNHIPTI-OXVORJCQSA-N |
| PubChem CID | 124080936 |
| IUPAC Name | (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride |
| SMILES | CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6125103
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Thermo Scientific Chemicals
J6125103 |
1 g |
Each for $105.59
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AAJ6125106
|
Thermo Scientific Chemicals
J6125106 |
5 g |
Each for $365.10
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AAJ6125114
|
Thermo Scientific Chemicals
J6125114 |
25 g |
Each for $1,474.67
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Description
Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
- Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA
Application
- Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
- It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
- It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus
Chemical Identifiers
| 859-18-7 | |
| 442.996 | |
| POUMFISTNHIPTI-OXVORJCQSA-N | |
| (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride |
| C18H35ClN2O6S | |
| MFCD00058237 | |
| 124080936 | |
| CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl |
Specifications
| Lincomycin Hydrochloride | |
| 859-18-7 | |
| 1 g | |
| MFCD00058237 | |
| Soluble in water | |
| CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl | |
| 442.996 | |
| 443 |
| Crystalline Powder | |
| White | |
| C18H35ClN2O6S | |
| 4171650 | |
| POUMFISTNHIPTI-OXVORJCQSA-N | |
| (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride | |
| 124080936 | |
| Lincomycin hydrochloride |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 212-726-7
RTECSNumber : RH6315000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only