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ITGAM Rabbit anti-Human, Clone:RM290, Abnova™
Rabbit monoclonal antibody raised against human ITGAM.
Supplier: Abnova Corporation MAB16920
Description
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (′Mac-1′), or inactivated-C3b (iC3b) receptor 3 (′CR3′). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]Specifications
| ITGAM | |
| Monoclonal | |
| Unconjugated | |
| Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-200) Western Blot (1:200-500) The optimal working dilution should be determined by the end user. |
|
| ITGAM | |
| Rabbit | |
| 100 μL | |
| This antibody reacts to human CD11b (Integrin alpha-M). | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| RM290 | |
| integrin, alpha M (complement component 3 receptor 3 subunit) | |
| In PBS (50% glycerol, 1% BSA, 0.09% sodium azide) | |
| CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6 | |
| A peptide corresponding to C-terminus of human ITGAM. | |
| 3684 | |
| Human | |
| Antibody | |
| IgG |