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Invitrogen™ Human CFHR1 (aa 104-132) Control Fragment Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP104315

Catalog No. RP104315


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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58590 (PA5-58590. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Specifications

Specifications

Q03591
Blocking Assay, Control
3078
100 μL
AI194696; CFHL; Cfhl1; CFHL1P; CFHR1; CFHR1P; CFHRB; complement component factor h-like 1; complement factor H related 1; complement factor H-related 1; complement factor H-related 1 pseudogene; complement factor H-related protein; complement factor H-related protein 1; FHR1; FHR-1; H factor (complement)-like 1; H factor (complement)-like 2; h factor-like protein 1; H36; H36-1; H36-2; H-factor-like 1; HFL1; HFL2
CFHR1
Human
His-ABP-tag
-20°C, Avoid Freeze/Thaw Cycles
Liquid
≥5.0 mg/mL
1 M urea, PBS with no preservative; pH 7.4
Human CFHR1 (aa 104-132) Control Fragment
RUO
CFHR1
Unconjugated
Recombinant
HLEGDTVQIICNTGYRLQNNENNISCVER
E. coli
>80% by SDS-PAGE and Coomassie blue staining
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