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Invitrogen™ Human 20S Proteasome Z (aa 263-277) Synthetic Peptide

Synthetic Peptide

Supplier:  Invitrogen™ PEP175

Catalog No. PEP175


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Description

Description

Human 20S Proteasome Z (residues 263-277) Synthetic Peptide, PEP-175, from Invitrogen.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
Specifications

Specifications

5695
purified
Human 20 S Proteasome Z (aa 263-277)
-20°C. Avoid freeze-thaw cycles.
Lyophilized
Control
Lyophilized
Peptide
RUO - research use only
Human
Q99436
0.5 mg/mL
Synthetic Peptide
peptide with no preservative
PSMB7
No preservative
50 μg
C-E(263)-I-E-V-L-E-E-T-V-Q-T-M-D-T-S(NH2)(277)
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