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Invitrogen™ Human 20S Proteasome Z (aa 263-277) Synthetic Peptide
Synthetic Peptide
Supplier: Invitrogen™ PEP175
Description
Human 20S Proteasome Z (residues 263-277) Synthetic Peptide, PEP-175, from Invitrogen.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).Specifications
5695 | |
purified | |
Human 20 S Proteasome Z (aa 263-277) | |
-20°C. Avoid freeze-thaw cycles. | |
Lyophilized | |
Control | |
Lyophilized | |
Peptide | |
RUO - research use only |
Human | |
Q99436 | |
0.5 mg/mL | |
Synthetic Peptide | |
peptide with no preservative | |
PSMB7 | |
No preservative | |
50 μg | |
C-E(263)-I-E-V-L-E-E-T-V-Q-T-M-D-T-S(NH2)(277) |