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HTR2B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Fisher Scientific PA585605

Catalog No. PIPA585605


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Description

Description

Keep as concentrated solution. Positive Control: SH-SY5Y, SH-SY5Y membrane fraction extract, unboiled SH-SY5Y, unboiled SH-SY5Y membrane fraction extract, mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.
Specifications

Specifications

HTR2B
Polyclonal
Unconjugated
HTR2B
5-HT 2B receptor, 5-HT(2B), 5-HT2B, 5-HT-2B, 5HT2B Receptor, 5-HT2b receptor, 5-HT-2F, 5-hydroxytryptamine (serotonin) receptor 2B, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, 5-hydroxytryptamine 2B receptor, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2B variant b, AJ012488, AV377389, HTR2B, NP75 protein, serotonin receptor 2B, Srl, Stomach fundus serotonin receptor
Rabbit
Antigen affinity chromatography
RUO
15559, 3357
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
2.29 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
P41595, Q02152
HTR2B
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human 5-HT2B receptor.
100 μL
Primary
Human, Mouse
Antibody
IgG
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