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HIF-2 alpha Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Fisher Scientific PA116510
Description
Suggested positive control: Cos7 CoCl2-treated nuclear extract, PC12 nuclear extracts.
HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.Specifications
| HIF-2 alpha | |
| Polyclonal | |
| Unconjugated | |
| EPAS1 | |
| basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100348809, 100771160, 13819, 2034, 29452, 443286 | |
| -20°C | |
| Liquid |
| ChIP Assay, ELISA, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Western Blot | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| P97481, Q99814, Q9JHS1 | |
| EPAS1 | |
| A peptide derived from the C-terminus of mouse/human HIF-2 alpha protein. | |
| 100 μL | |
| Primary | |
| Fish, Hamster, Human, Mouse, Non-human Primate, Ovine, Rabbit, Rat, Reptile | |
| Antibody | |
| IgG |