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Tocris Bioscience™ GSK 269962 DFS Item

Potent and selective ROCK inhibitor

Supplier:  Tocris Bioscience™ 400950

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Catalog No. 4009500


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Description

Description

Potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricted rat aorta (IC50 = 35 nM); lowers blood pressure in a rat model of hypertension.
Specifications

Specifications

GSK 269962
50 mg
570.6
570.61
850664-21-0
C29H30N8O5
>99%

Chemical Identifiers

850664-21-0
C29H30N8O5
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Safety and Handling

Safety and Handling

Recommended Storage : Store at +4°C

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