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Fumonisin B1, 96%
Fumonisin, CAS # 116355-83-0, also known as Macrofusine, is a cell permeable mycotoxin that is an inhibitor of sphingosine N-acetyl transferase. | CAS: 116355-83-0 | C34H59NO15 | 721.8 g/mol
$372.88 - $1629.47
Chemical Identifiers
| CAS | 116355-83-0 |
|---|---|
| Molecular Formula | C34H59NO15 |
| Molecular Weight (g/mol) | 721.8 |
| MDL Number | MFCD00133349 |
| InChI Key | UVBUBMSSQKOIBE-UWCNXKJPSA-N |
| Synonym | macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid |
| PubChem CID | 16760030 |
| IUPAC Name | (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
| SMILES | CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AC328250010
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Thermo Scientific Chemicals
328250010 |
1 mg |
Each for $372.88
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AC328250050
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Thermo Scientific Chemicals
328250050 |
5 mg |
Each for $1,629.47
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Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fumonisin is a fungal metabolite that is a cell permeable mycotoxin that can halt sphingolipid biosynthesis by inhibiting sphingosine N-acetyl transferase
Applications
• It can potently inhibit sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases
• It is also a protein serine and threonine phosphatase inhibitor
• It can selectively inhibit sphingomyelin biosynthesis in neuronal cells
Chemical Identifiers
| 116355-83-0 | |
| 721.8 | |
| UVBUBMSSQKOIBE-UWCNXKJPSA-N | |
| 16760030 | |
| CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O |
| C34H59NO15 | |
| MFCD00133349 | |
| macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
Specifications
| 116355-83-0 | |
| 55.00 to 58.00%C, 1.60 to 2.20%N | |
| C34H59NO15 | |
| 1 mg | |
| macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| UVBUBMSSQKOIBE-UWCNXKJPSA-N | |
| (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid | |
| 16760030 | |
| 96% | |
| Fumonisin B1 |
| Tan to White | |
| 95% min. (HPLC) | |
| MFCD00133349 | |
| 15, 4318 | |
| Solubility in water: soluble. Other solubilities: soluble in methanol,acetonitrile | |
| CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O | |
| 721.8 | |
| 721.8 | |
| Powder |
Safety and Handling
GHS H Statement:
Suspected of causing cancer.
GHS P Statement:
Use personal protective equipment as required.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
RUO – Research Use Only