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Forskolin, 98+%
Forskolin, CAS # 66575-29-9, is a diterpenoid compound isolated from Indian Coleus that acts as a strong activator of the adenylate cyclase system. | CAS: 66575-29-9 | C22H34O7 | 410.507 g/mol
$374.25 - $1364.58
Chemical Identifiers
| CAS | 66575-29-9 |
|---|---|
| Molecular Formula | C22H34O7 |
| Molecular Weight (g/mol) | 410.507 |
| MDL Number | MFCD00082317 |
| InChI Key | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
| Synonym | forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish |
| PubChem CID | 47936 |
| ChEBI | CHEBI:42471 |
| IUPAC Name | [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate |
| SMILES | CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ63292MA
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Thermo Scientific Chemicals
J63292MA |
10 mg |
Each for $374.25
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AAJ63292MF
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Thermo Scientific Chemicals
J63292MF |
50 mg |
Each for $1,364.58
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Description
Forskolin acts as an adenylyl cyclase activator. It is used in the treatment of hypertension, asthma, eczema, psoriasis, congestive heart failure, angina, stomachache, gastric and intestinal spasm. It also plays an important role in the treatment of rheumatism, heart, blood and circulation conditions and cancers. It is used to induce menstruation and as an oral contraceptive.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite
• It is a protein kinase A agonist and a cyclic ketone • Forskolin is an antihypertensive and muscle relaxant; it can also promote the release of pituitary hormones and prevent platelet aggregation
Application
• Forskolin assists in neuron differentiation in vitro
• Useful for studies of cell metabolism and development; there is some evidence of its usefulness in the study of glaucoma
• It is intended for cell culture and biochemistry applications
Chemical Identifiers
| 66575-29-9 | |
| 410.507 | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| 47936 | |
| [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate |
| C22H34O7 | |
| MFCD00082317 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| CHEBI:42471 | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
Specifications
| 66575-29-9 | |
| C22H34O7 | |
| 10 mg | |
| 14,2476 | |
| Soluble in ethanol,dimethylsulfoxide and chloroform; Insolule in water. | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O | |
| 410.507 | |
| CHEBI:42471 | |
| ≥98% | |
| Forskolin |
| White | |
| MFCD00082317 | |
| 1692716 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate | |
| 47936 | |
| 410.51 | |
| Solid |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P280-P302+P352-P312-P363-P501c
H312
EINECSNumber : 266-410-9
RTECSNumber : QL6150000
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only