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Ethacrynic acid
CAS: 58-54-8 | C13H12Cl2O4 | 303.135 g/mol
Supplier: Thermo Scientific Chemicals J6368403
Description
Ethacrynic acid is used to inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsEthacrynic acid is used to inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, in
Specifications
| Ethacrynic acid | |
| White | |
| MFCD00056693 | |
| 14,3717 | |
| Soluble in ethanol,chloroform,ether,ammonia,carbonates,and methanol. Insoluble in water. | |
| CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl | |
| 303.135 | |
| CHEBI:4876 | |
| Crystalline Powder |
| 58-54-8 | |
| C13H12Cl2O4 | |
| 1 g | |
| ethacrynic acid, etacrynic acid, ethacrynate, etacrinic acid, hydromedin, edecrin, crinuryl, edecril, edecrina, endecril | |
| AVOLMBLBETYQHX-UHFFFAOYSA-N | |
| 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid | |
| 3278 | |
| 303.14 |
Chemical Identifiers
| 58-54-8 | |
| 303.135 | |
| AVOLMBLBETYQHX-UHFFFAOYSA-N | |
| 3278 | |
| 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid |
| C13H12Cl2O4 | |
| MFCD00056693 | |
| ethacrynic acid, etacrynic acid, ethacrynate, etacrinic acid, hydromedin, edecrin, crinuryl, edecril, edecrina, endecril | |
| CHEBI:4876 | |
| CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302+H312+H332-H315-H319-H335
EINECSNumber : 200-384-1
RTECSNumber : AG6600000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only