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Domperidone
Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier | CAS: 57808-66-9 | C22H24ClN5O2 | 425.917 g/mol
$218.90 - $824.40
Chemical Identifiers
| CAS | 57808-66-9 |
|---|---|
| Molecular Formula | C22H24ClN5O2 |
| Molecular Weight (g/mol) | 425.917 |
| MDL Number | MFCD00069256 |
| InChI Key | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
| Synonym | domperidone, motilium, nauzelin, domperidonum, domperidona, domperidon, domperidonum inn-latin, domperidona inn-spanish, motillium, motinorm |
| PubChem CID | 3151 |
| ChEBI | CHEBI:31515 |
| IUPAC Name | 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| SMILES | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ63681MC
|
Thermo Scientific Chemicals
J63681MC |
100 mg |
Each for $218.90
|
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AAJ63681ME
|
Thermo Scientific Chemicals
J63681ME |
500 mg |
Each for $824.40
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Description
Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDomperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Chemical Identifiers
| 57808-66-9 | |
| 425.917 | |
| FGXWKSZFVQUSTL-UHFFFAOYSA-N | |
| 3151 | |
| 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| C22H24ClN5O2 | |
| MFCD00069256 | |
| domperidone, motilium, nauzelin, domperidonum, domperidona, domperidon, domperidonum inn-latin, domperidona inn-spanish, motillium, motinorm | |
| CHEBI:31515 | |
| C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
Specifications
| 57808-66-9 | |
| White | |
| MFCD00069256 | |
| 14,3418 | |
| Slightly soluble in water. | |
| C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O | |
| 425.917 | |
| CHEBI:31515 | |
| Crystalline Powder |
| 243°C | |
| C22H24ClN5O2 | |
| 100 mg | |
| domperidone, motilium, nauzelin, domperidonum, domperidona, domperidon, domperidonum inn-latin, domperidona inn-spanish, motillium, motinorm | |
| FGXWKSZFVQUSTL-UHFFFAOYSA-N | |
| 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one | |
| 3151 | |
| 425.91 | |
| Domperidone |
Safety and Handling
GHS H Statement
H361
Suspected of damaging fertility or the unborn child.
P201-P202-P281-P308+P313-P501c
H361
EINECSNumber : 260-968-7
RTECSNumber : DE2275900
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only