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DL-Thioctic acid, 98%
DL-Thioctic acid, CAS # 1077-28-7, is an antioxidant and coenzyme important for the activity of enzymes. | CAS: 1077-28-7 | C8H14O2S2 | 206.32 g/mol
$147.48 - $513.63
Chemical Identifiers
| CAS | 1077-28-7 |
|---|---|
| Molecular Formula | C8H14O2S2 |
| Molecular Weight (g/mol) | 206.32 |
| MDL Number | MFCD00005474 |
| InChI Key | AGBQKNBQESQNJD-UHFFFAOYNA-N |
| Synonym | dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid |
| PubChem CID | 864 |
| ChEBI | CHEBI:16494 |
| IUPAC Name | 5-(1,2-dithiolan-3-yl)pentanoic acid |
| SMILES | OC(=O)CCCCC1CCSS1 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAL0471106
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Thermo Scientific Chemicals
L0471106 |
5 g |
Each for $147.48
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AAL0471114
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Thermo Scientific Chemicals
L0471114 |
25 g |
Each for $513.63
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Description
DL-Thioctic acid plays an essential role in aerobic metabolism. Further, it acts as a free radical scavenger.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• DL-Thioctic acid derives from octanoic acid, and it has been described as an antioxidant coenzyme important for the activity of enzyme complexes including pyruvate dehydrogenase and glycine decarboxylase
Application
• DL-Thioctic acid has been used in studies to increase insulin sensitivity and stimulate glucose uptake into adipose and muscle cells in vitro
• DL-Thioctic acid has an essential role in aerobic metabolism
• It has been used as free radical scavenger compound
• It can also assist in repairing oxidative damage via the increase of endogenous antioxidants, including vitamins C, vitamin E, and glutathione
• It can induce apoptosis through caspase-independent and caspase-dependent pathways, a process mediated by intracellular Ca2+
• DL-Thioctic acid has the ability to impact various cellular biological pathways since it can increase glutathione synthesis and modulate transcription factor activity, mainly nuclear factor kappa B (NF-κB)
• It can decrease the phagocytosis of myelin by macrophages
Chemical Identifiers
| 1077-28-7 | |
| 206.32 | |
| AGBQKNBQESQNJD-UHFFFAOYNA-N | |
| 864 | |
| 5-(1,2-dithiolan-3-yl)pentanoic acid |
| C8H14O2S2 | |
| MFCD00005474 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| CHEBI:16494 | |
| OC(=O)CCCCC1CCSS1 |
Specifications
| 1077-28-7 | |
| 160°C to 165°C | |
| MFCD00005474 | |
| 81853 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| AGBQKNBQESQNJD-UHFFFAOYNA-N | |
| 5-(1,2-dithiolan-3-yl)pentanoic acid | |
| 864 | |
| 206.33 | |
| DL-Thioctic acid |
| 59°C to 63°C | |
| C8H14O2S2 | |
| 5 g | |
| 14,9326 | |
| Soluble in methanol,ethanol,diethyl ether and chloroform. Insoluble in water. | |
| OC(=O)CCCCC1CCSS1 | |
| 206.32 | |
| CHEBI:16494 | |
| 98% |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 214-071-2
RTECSNumber : JP1192000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only