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Diphenyl phosphorochloridate, 97%
CAS: 2524-64-3 | C12H10ClO3P | 268.633 g/mol
Supplier: Thermo Scientific Chemicals A1354618
Description
Diphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5',5'-triphosphate, guanosine-cytidine-5',5'-triphosphate, guanosine-uridine-5',5'-triphosphate, diguanosine-5',5'-diphosphate and diguanosine-5',5'-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDiphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.
Solubility
Immiscible with water.
Notes
Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.
Specifications
| Diphenyl phosphorochloridate | |
| 1.296 | |
| 113°C (235°F) | |
| 1.55 | |
| 50 g | |
| 654130 | |
| diphenyl chlorophosphate, diphenyl phosphorochloridate, diphenylchlorophosphate, phosphorochloridic acid, diphenyl ester, chlorodiphenyl phosphate, o,o-diphenyl chlorophosphate, chlorodiphenoxyphosphine oxide, diphenoxychlorophosphine oxide, diphenyl chlorophosphonate, diphenylphosphoric acid monochloride | |
| BHIIGRBMZRSDRI-UHFFFAOYSA-N | |
| [chloro(phenoxy)phosphoryl]oxybenzene | |
| 75654 | |
| 97% |
| 2524-64-3 | |
| 145°C to 147°C (1 mmHg) | |
| C12H10ClO3P | |
| MFCD00003030 | |
| UN3265 | |
| Moisture sensitive | |
| Immiscible with water. | |
| C1=CC=C(C=C1)OP(=O)(OC2=CC=CC=C2)Cl | |
| 268.633 | |
| 268.64 |
Chemical Identifiers
| 2524-64-3 | |
| 268.633 | |
| BHIIGRBMZRSDRI-UHFFFAOYSA-N | |
| 75654 | |
| C1=CC=C(C=C1)OP(=O)(OC2=CC=CC=C2)Cl |
| C12H10ClO3P | |
| MFCD00003030 | |
| diphenyl chlorophosphate, diphenyl phosphorochloridate, diphenylchlorophosphate, phosphorochloridic acid, diphenyl ester, chlorodiphenyl phosphate, o,o-diphenyl chlorophosphate, chlorodiphenoxyphosphine oxide, diphenoxychlorophosphine oxide, diphenyl chlorophosphonate, diphenylphosphoric acid monochloride | |
| [chloro(phenoxy)phosphoryl]oxybenzene |
Safety and Handling
GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
H314
DOTInformation : Hazard Class: 8; Packaging Group: II
EINECSNumber : 219-759-6
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only