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cis-4-Hydroxy-L-proline, 99%
CAS: 618-27-9 | C5H9NO3 | 131.13 g/mol
$336.45 - $932.41
Chemical Identifiers
| CAS | 618-27-9 |
|---|---|
| Molecular Formula | C5H9NO3 |
| Molecular Weight (g/mol) | 131.13 |
| MDL Number | MFCD00064319,MFCD00064320 |
| InChI Key | PMMYEEVYMWASQN-IMJSIDKUSA-N |
| Synonym | cis-4-hydroxy-l-proline, 2s,4s-4-hydroxypyrrolidine-2-carboxylic acid, l-hydroxyproline, l-allohydroxyproline, allo-4-hydroxy-l-proline, cis-4-hydroxyproline, 4s-4-hydroxy-l-proline, l-cis-4-hydroxyproline, l-allo-hydroxyproline, l-proline, 4-hydroxy-, 4s |
| PubChem CID | 440015 |
| ChEBI | CHEBI:28397 |
| IUPAC Name | (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid |
| SMILES | O[C@@H]1CN[C@@H](C1)C(O)=O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAH27194MD
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Thermo Scientific Chemicals
H27194MD |
250 mg |
Each for $336.45
|
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AAH2719403
|
Thermo Scientific Chemicals
H2719403 |
1 g |
Each for $932.41
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Description
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Chemical Identifiers
| 618-27-9 | |
| 131.13 | |
| PMMYEEVYMWASQN-IMJSIDKUSA-N | |
| 440015 | |
| (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid |
| C5H9NO3 | |
| MFCD00064319,MFCD00064320 | |
| cis-4-hydroxy-l-proline, 2s,4s-4-hydroxypyrrolidine-2-carboxylic acid, l-hydroxyproline, l-allohydroxyproline, allo-4-hydroxy-l-proline, cis-4-hydroxyproline, 4s-4-hydroxy-l-proline, l-cis-4-hydroxyproline, l-allo-hydroxyproline, l-proline, 4-hydroxy-, 4s | |
| CHEBI:28397 | |
| O[C@@H]1CN[C@@H](C1)C(O)=O |
Specifications
| ∽250°C (decomposition) | |
| C5H9NO3 | |
| cis-4-hydroxy-l-proline, 2s,4s-4-hydroxypyrrolidine-2-carboxylic acid, l-hydroxyproline, l-allohydroxyproline, allo-4-hydroxy-l-proline, cis-4-hydroxyproline, 4s-4-hydroxy-l-proline, l-cis-4-hydroxyproline, l-allo-hydroxyproline, l-proline, 4-hydroxy-, 4s | |
| PMMYEEVYMWASQN-IMJSIDKUSA-N | |
| (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid | |
| 131.13 | |
| CHEBI:28397 | |
| 131.13 | |
| cis-4-Hydroxy-L-proline |
| 618-27-9 | |
| MFCD00064319,MFCD00064320 | |
| Soluble in water. | |
| O[C@@H]1CN[C@@H](C1)C(O)=O | |
| 250 mg | |
| 440015 | |
| −59° (c=2 in Water) | |
| 99% |
Safety and Handling
EINECSNumber : 210-542-1
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only