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Cimetidine, 98+%
H2 histamine receptor antagonist | CAS: 51481-61-9 | C10H16N6S | 252.34 g/mol
$148.90 - $501.11
Chemical Identifiers
| CAS | 51481-61-9 |
|---|---|
| Molecular Formula | C10H16N6S |
| Molecular Weight (g/mol) | 252.34 |
| MDL Number | MFCD00133296 |
| InChI Key | AQIXAKUUQRKLND-UHFFFAOYSA-N |
| Synonym | cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine |
| PubChem CID | 2756 |
| ChEBI | CHEBI:3699 |
| IUPAC Name | 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine |
| SMILES | CC1=C(N=CN1)CSCCNC(=NC)NC#N |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6282506
|
Thermo Scientific Chemicals
J6282506 |
5 g |
Each for $148.90
|
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AAJ6282509
|
Thermo Scientific Chemicals
J6282509 |
10 g |
Each for $236.23
|
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AAJ6282514
|
Thermo Scientific Chemicals
J6282514 |
25 g |
Each for $501.11
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Description
Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).
Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Chemical Identifiers
| 51481-61-9 | |
| 252.34 | |
| AQIXAKUUQRKLND-UHFFFAOYSA-N | |
| 2756 | |
| 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine |
| C10H16N6S | |
| MFCD00133296 | |
| cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine | |
| CHEBI:3699 | |
| CC1=C(N=CN1)CSCCNC(=NC)NC#N |
Specifications
| 51481-61-9 | |
| White | |
| MFCD00133296 | |
| 14,2279 | |
| Soluble to 50 mM in water and to 100 mM in DMSO,solubility in HCl (almost transparency). | |
| CC1=C(N=CN1)CSCCNC(=NC)NC#N | |
| 252.34 | |
| CHEBI:3699 | |
| ≥98% | |
| Cimetidine |
| 139°C to 144°C | |
| C10H16N6S | |
| 5 g | |
| cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine | |
| AQIXAKUUQRKLND-UHFFFAOYSA-N | |
| 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine | |
| 2756 | |
| 252.34 | |
| Powder |
Safety and Handling
GHS H Statement
H360
May damage fertility or the unborn child.
P201-P202-P281-P308+P313-P501c
H360
EINECSNumber : 257-232-2
RTECSNumber : MF0035500
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only