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Cephalothin sodium salt

A first-generation cephalosporin antibiotic | CAS: 58-71-9 | C16H15N2NaO6S2 | 418.414 g/mol

$187.92 - $646.07

Chemical Identifiers

CAS 58-71-9
Molecular Formula C16H15N2NaO6S2
Molecular Weight (g/mol) 418.414
MDL Number MFCD00072025
InChI Key VUFGUVLLDPOSBC-XRZFDKQNSA-M
Synonym 7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
PubChem CID 23675321
ChEBI CHEBI:3542
IUPAC Name sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
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Products 2
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AAJ6560703
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Thermo Scientific Chemicals
J6560703
1 g
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AAJ6560706
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Thermo Scientific Chemicals
J6560706
5 g
Each for $646.07
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Description

Description

Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

Solubility
Soluble in water

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications

Chemical Identifiers

58-71-9
418.414
VUFGUVLLDPOSBC-XRZFDKQNSA-M
23675321
sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
C16H15N2NaO6S2
MFCD00072025
7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
CHEBI:3542
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]

Specifications

Cephalothin Sodium Salt
58-71-9
White
C16H15N2NaO6S2
4120706
7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
VUFGUVLLDPOSBC-XRZFDKQNSA-M
sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
23675321
418.42
Powder
Odorless
1 g
MFCD00072025
14,1982
Soluble in water
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
418.414
CHEBI:3542
Cephalothin sodium salt
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Safety and Handling

Safety and Handling

GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.

P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c

H315-H317-H319-H334-H335

EINECSNumber : 200-394-6

RTECSNumber : XI0388300

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only