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Cytiva Capto™ Core 400
Designed for intermediate purification and polishing of viruses and other large biomolecules.
Supplier: Cytiva 17372401
Description
Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin.
- Significantly improved productivity enabled by up to 100âfold higher sample load and significantly higher flow rates compared with SEC.
- Bead with ligandâactivated core and inactive shell allows efficient capture of impurities, while target molecules are collected in the flowthrough.
- Straightforward optimization due to flow-through chromatography and robust performance, allowing for a wide window of operation.
Capto Core 400 is an excellent alternative to sizeâexclusion chromatography (SEC) resins that are typically employed in the final stages of virus purification in vaccine manufacture.
Specifications
1 M sodium hydroxide (NaOH), 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol | |
Agarose Chromatography Resin | |
Virus | |
20 cm | |
Octylamine | |
90 μm | |
22 mg | |
Retrovirus | |
400,000 |
Chromatography Resin | |
25 mL | |
Each | |
700 cm/hr. | |
3 to 14 | |
4°C to 30°C | |
Virus | |
Tricorn Column | |
Multimodal Resin |