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Cytiva Capto™ Core 400

Designed for intermediate purification and polishing of viruses and other large biomolecules.

Supplier:  Cytiva 17372401

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Catalog No. 09-928-203


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Description

Description

Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin.

  • Significantly improved productivity enabled by up to 100‐fold higher sample load and significantly higher flow rates compared with SEC.
  • Bead with ligand‐activated core and inactive shell allows efficient capture of impurities, while target molecules are collected in the flowthrough.
  • Straightforward optimization due to flow-through chromatography and robust performance, allowing for a wide window of operation.

Capto Core 400 is an excellent alternative to size‐exclusion chromatography (SEC) resins that are typically employed in the final stages of virus purification in vaccine manufacture.

Specifications

Specifications

1 M sodium hydroxide (NaOH), 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol
Agarose Chromatography Resin
Virus
20 cm
Octylamine
90 μm
22 mg
Retrovirus
400,000
Chromatography Resin
25 mL
Each
700 cm/hr.
3 to 14
4°C to 30°C
Virus
Tricorn Column
Multimodal Resin
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