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Thermo Scientific Chemicals Calpeptin, ≥98%

Inhibitor of the calcium-dependent protease calpain and cathepsin L

$386.56 - $386.56

Chemical Identifiers

CAS 117591-20-5
Molecular Formula C20H30N2O4
Synonym N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal
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Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60481MA
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Thermo Scientific Chemicals
J60481MA
10 mg
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Description

Description

Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

117591-20-5
C20H30N2O4
N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal

Specifications

10 mg
-30°C to -10°C
117591-20-5
362.50g/mol
Soluble in DMSO at 15mg/ml
Powder
CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
362.47
White
Inhibitor of the calcium-dependent protease calpain and cathepsin L
C20H30N2O4
N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal
Signal Transduction Reagent
PGGUOGKHUUUWAF-ROUUACIJSA-N
benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxohexan-2-yl]carbamoyl}butyl]carbamate
≥98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
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RUO – Research Use Only