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Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate
CAS: 501-53-1 | C8H7ClO2 | 170.592 g/mol
Supplier: Thermo Scientific Chemicals A1568230
Description
Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsBenzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.
Solubility
Miscible with ether, acetone and benzene.
Notes
Store in cool place. Moisture sensitive.
Specifications
| Benzyl chloroformate | |
| 501-53-1 | |
| 1.195 | |
| 125°C (257°F) | |
| C8H7ClO2 | |
| MFCD00000640 | |
| UN1739 | |
| 14,1801 | |
| Miscible with ether,acetone and benzene. | |
| C1=CC=C(C=C1)COC(=O)Cl | |
| 170.592 | |
| 170.6 |
| stabilized with ≈0.1% sodium carbonate | |
| -20°C | |
| 178°C to 180°C | |
| Acrid | |
| 1.517 | |
| 250 g | |
| Moisture sensitive | |
| benzyl chloroformate, carbobenzoxy chloride, benzyl chlorocarbonate, cbz chloride, benzyloxycarbonyl chloride, carbobenzyloxy chloride, carbonochloridic acid, phenylmethyl ester, benzylcarbonyl chloride, cbz-cl, chloroformic acid, benzyl ester | |
| HSDAJNMJOMSNEV-UHFFFAOYSA-N | |
| benzyl carbonochloridate | |
| 10387 | |
| 95% |
Chemical Identifiers
| 501-53-1 | |
| 170.592 | |
| HSDAJNMJOMSNEV-UHFFFAOYSA-N | |
| 10387 | |
| C1=CC=C(C=C1)COC(=O)Cl |
| C8H7ClO2 | |
| MFCD00000640 | |
| benzyl chloroformate, carbobenzoxy chloride, benzyl chlorocarbonate, cbz chloride, benzyloxycarbonyl chloride, carbobenzyloxy chloride, carbonochloridic acid, phenylmethyl ester, benzylcarbonyl chloride, cbz-cl, chloroformic acid, benzyl ester | |
| benzyl carbonochloridate |
Safety and Handling
GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
P201-P202-P210-P234-P235-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P390-P501c
H227-H290-H303-H314-H332-H335-H336-H350-H373
DOTInformation : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: BENZYL CHLOROFORMATE
EINECSNumber : 207-925-0
RTECSNumber : LQ5860000
TSCA : Yes
Recommended Storage : Store at -20°C
RUO – Research Use Only