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FGR, Mouse, Clone: 1B12, Abnova™

Mouse monoclonal antibody raised against a partial recombinant FGR.

Supplier:  Abnova Corporation H00002268M03

Catalog No. 89-022-100


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Description

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Sequence: MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEA
Specifications

Specifications

FGR
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC064382
FGR
FGR (AAH64382, 1 a.a. ∼ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG2a κ
ELISA, Immunohistochemistry (PFA fixed), Western Blot
1B12
Mouse monoclonal antibody raised against a partial recombinant FGR.
FGR
FLJ43153/MGC75096/SRC2/c-fgr/c-src2/p55c-fgr/p58c-fgr
Mouse
Affinity chromatography
RUO
2268
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liquid
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