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FDPS, Mouse, Clone: 3A6, Abnova™
Mouse monoclonal antibody raised against a partial recombinant FDPS.
Supplier: Abnova Corporation H00002224M01
Description
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
Sequence: VTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRKSpecifications
| FDPS | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_002004 | |
| FDPS | |
| FDPS (NP_001995.1, 320 a.a. ∼ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA | |
| 3A6 | |
| Mouse monoclonal antibody raised against a partial recombinant FDPS. | |
| FDPS | |
| FPPS/FPS | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 2224 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |