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6-Mercaptopurine monohydrate, 98%
CAS: 6112-76-1 | C5H6N4OS | 170.19 g/mol
Supplier: Thermo Scientific Chemicals A1219706
Description
6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
Solubility
Soluble in dilute solutions of alkali hydroxides, hot alcohol, and 1 N NaOH (50 mg/ml). Insoluble in water.
Notes
Store in cool, dry place, in well sealed container. Store away from oxidizing agents.
Specifications
| 6-Mercaptopurine monohydrate | |
| ∼315°C (decomposition) | |
| MFCD03854445,MFCD01461928 | |
| 4012091 | |
| 6-mercaptopurine monohydrate, 6-mercaptopurine hydrate, mercaptopurine monohydrate, mercaptopurine hydrate, 6h-purine-6-thione, 1,7-dihydro-, monohydrate, 6,7-dihydro-3h-purine-6-thione hydrate, purine-6-thiol monohydrate, 1,7-dihydro-6h-purine-6-thione monohydrate, purine-6-thiol, monohydrate, unii-e7wed276i5 | |
| WFFQYWAAEWLHJC-UHFFFAOYSA-N | |
| 3,7-dihydropurine-6-thione;hydrate | |
| 2724350 | |
| 170.19 (152.17 Anhydrous) |
| 6112-76-1 | |
| C5H6N4OS | |
| 5 g | |
| 14,5871 | |
| Soluble in dilute solutions of alkali hydroxides,hot alcohol,and 1 N NaOH (50mg/ml). Insoluble in water. | |
| O.S=C1N=CNC2=C1NC=N2 | |
| 170.19 | |
| CHEBI:31822 | |
| 98% |
Chemical Identifiers
| 6112-76-1 | |
| 170.19 | |
| WFFQYWAAEWLHJC-UHFFFAOYSA-N | |
| 2724350 | |
| 3,7-dihydropurine-6-thione;hydrate |
| C5H6N4OS | |
| MFCD03854445,MFCD01461928 | |
| 6-mercaptopurine monohydrate, 6-mercaptopurine hydrate, mercaptopurine monohydrate, mercaptopurine hydrate, 6h-purine-6-thione, 1,7-dihydro-, monohydrate, 6,7-dihydro-3h-purine-6-thione hydrate, purine-6-thiol monohydrate, 1,7-dihydro-6h-purine-6-thione monohydrate, purine-6-thiol, monohydrate, unii-e7wed276i5 | |
| CHEBI:31822 | |
| O.S=C1N=CNC2=C1NC=N2 |
Safety and Handling
GHS H Statement
H341-H361-H302
Suspected of causing genetic defects.
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.
P202-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335-H341-H361
EINECSNumber : 200-037-4
RTECSNumber : UP0400000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only