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5-Bromo-2'-deoxyuridine, 99%

CAS: 59-14-3 | C9H11BrN2O5 | 307.10 g/mol

Supplier:  Thermo Scientific Chemicals H27260MD

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Catalog No. AAH27260MD


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Description

Description

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Specifications

Specifications

5-Bromo-2'-deoxyuridine
∽190°C (decomposition)
MFCD00006529
30395
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
WOVKYSAHUYNSMH-RRKCRQDMSA-N
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O
307.10
CHEBI:472552
99%
59-14-3
C9H11BrN2O5
250 mg
14,1452
Soluble in water.
+31° (c=1 in 0.1N HCl)
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
6035
307.1

Chemical Identifiers

59-14-3
307.10
WOVKYSAHUYNSMH-RRKCRQDMSA-N
6035
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
C9H11BrN2O5
MFCD00006529
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
CHEBI:472552
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O
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Safety and Handling

Safety and Handling

GHS H Statement
H341
Suspected of causing genetic defects.

P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c

H315-H319-H335-H341

EINECSNumber : 200-415-9

RTECSNumber : YU7350000

TSCA : Yes

Recommended Storage : Keep cold

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