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5,7-Dihydroxy-4'-methoxyisoflavone, 98%

CAS: 491-80-5 | C16H12O5 | 284.27 g/mol

Supplier:  Thermo Scientific Chemicals 04385303

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Numéro de catalogue. AA4385303


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Description

Description

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Spécifications

Spécifications

5,7-Dihydroxy-4'-methoxyisoflavone
210°C to 213°C
MFCD00006839
278107
Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
284.27
CHEBI:17574
98%
491-80-5
C16H12O5
1 g
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
WUADCCWRTIWANL-UHFFFAOYSA-N
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
5280373
284.27
Powder

Identifiants chimiques

491-80-5
284.27
WUADCCWRTIWANL-UHFFFAOYSA-N
5280373
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
C16H12O5
MFCD00006839
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
CHEBI:17574
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
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missing translation for 'einecsNumber' : 207-744-7

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

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