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5,5'-Dithiobis(2-nitrobenzoic acid), 99%

CAS: 69-78-3 | C14H8N2O8S2 | 396.34 g/mol

Supplier:  Thermo Scientific Chemicals A1433106

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Catalog No. AAA1433106


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Description

Description

Reagent for determination of sufhydryl groups.5,5'-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent for determination of sufhydryl groups.5,5′-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.

Solubility
Soluble in water and ethanol.

Notes
Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.
Specifications

Specifications

5,5'-Dithiobis(2-nitrobenzoic acid)
∼240°C (decomposition)
MFCD00007140
1896821
Soluble in water and ethanol.
OC(=O)C1=CC(SSC2=CC=C(C(=C2)C(O)=O)[N+]([O-])=O)=CC=C1[N+]([O-])=O
396.34
CHEBI:86228
99%
69-78-3
C14H8N2O8S2
5 g
dtnb, 5,5'-dithiobis 2-nitrobenzoic acid, ellman's reagent, 3-carboxy-4-nitrophenyl disulfide, dithionitrobenzoic acid, dithiobisnitrobenzoic acid, 5,5'-disulfanediylbis 2-nitrobenzoic acid, benzoic acid, 3,3'-dithiobis 6-nitro, 3,3'-dithiobis 6-nitrobenzoic acid, 5,5'-dithio-bis 2-nitrobenzoic acid
KIUMMUBSPKGMOY-UHFFFAOYSA-N
5-[(3-carboxy-4-nitrophenyl)disulfanyl]-2-nitrobenzoic acid
6254
396.36

Chemical Identifiers

69-78-3
396.34
KIUMMUBSPKGMOY-UHFFFAOYSA-N
6254
5-[(3-carboxy-4-nitrophenyl)disulfanyl]-2-nitrobenzoic acid
C14H8N2O8S2
MFCD00007140
dtnb, 5,5'-dithiobis 2-nitrobenzoic acid, ellman's reagent, 3-carboxy-4-nitrophenyl disulfide, dithionitrobenzoic acid, dithiobisnitrobenzoic acid, 5,5'-disulfanediylbis 2-nitrobenzoic acid, benzoic acid, 3,3'-dithiobis 6-nitro, 3,3'-dithiobis 6-nitrobenzoic acid, 5,5'-dithio-bis 2-nitrobenzoic acid
CHEBI:86228
OC(=O)C1=CC(SSC2=CC=C(C(=C2)C(O)=O)[N+]([O-])=O)=CC=C1[N+]([O-])=O
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

EINECSNumber : 200-714-4

RTECSNumber : DG9650000

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS
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