missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Phenylpropanoids and polyketides
  6. Tetracyclines
  7. AC257711000

Thermo Scientific Chemicals 4-Epioxytetracycline, 'can be used as secondary standard'

4-Epioxytetracycline, CAS # 14206-58-7, is one of the main oxytetracycline metabolites that show antibacterial activity.

Supplier:  Thermo Scientific Chemicals 257711000

Catalog No. AC257711000


Only null left
Explore available promotions

Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 4-Epioxytetracycline is a metabolite of the oxytetracycline compound that displays antibacterial activity
  • It is the main degradation product derived from the oxytetracycline metabolization and has been detected in some biological samples
  • Its mechanism of action has been described to be related to the mitochondrial protein synthesis inhibition

Applications

  • In laboratory research it has been described that the treatment with 4-epioxytetracycline decreases the bacterial diversity of the intestinal microbiota and facilitates the proliferation of opportunistic pathogens in salmon
  • The use of 4-epioxytetracycline in animal models (wistar rats) resulted in a significant alteration of the gut microbiota and disorders in blood metabolomics
  • 4-Epioxytetracycline can be applied as a secondary reference standard during stability studies of oxytetracycline
  • 4-epioxytetracycline has been used in research studies to evaluate the degradation pathway and products of tetracyclines
Specifications

Specifications

4-Epioxytetracycline
14206-58-7
100.0
Beige-Green to Brown
80% min. (as is,calculated)
C22H24N2O9
100 mg
− 247.00
Solubility in water: 0.5g/L. Other solubilities: 3.6g/L methanol
CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
460.43
460.43
Powder
97%
96.0
168.0°C
Authentic
Glass bottle
MFCD00062825
10, 6846
4-epioxytetracyline, unii-73von8sry5, 4-epioxytetracycline, 73von8sry5, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide, hydroxy quatrimycin, oxytetracycline dihydrate specified impurity a ep, oxytetracycline hydrochloride specified impurity a ep, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 2-naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, 4r,4ar,5s,5ar,6s,12as
OWFJMIVZYSDULZ-DVJPNYBFSA-N
(4R,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
54678403
≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC)

Chemical Identifiers

14206-58-7
460.43
OWFJMIVZYSDULZ-DVJPNYBFSA-N
54678403
CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
C22H24N2O9
MFCD00062825
4-epioxytetracyline, unii-73von8sry5, 4-epioxytetracycline, 73von8sry5, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide, hydroxy quatrimycin, oxytetracycline dihydrate specified impurity a ep, oxytetracycline hydrochloride specified impurity a ep, 4r,4ar,5s,5ar,6s,12as-4-dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 2-naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, 4r,4ar,5s,5ar,6s,12as
(4R,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

GHS H Statement
Causes serious eye irritation.
Suspected of damaging the unborn child.

GHS P Statement
Wash face,hands and any exposed skin thoroughly after handling.
Wear protective gloves/protective clothing/eye protection/face protection.
Obtain special instructions before use.
IF exposed or concerned: Get medical

GHS Signal Word: Warning

Recommended Storage : 4°C

SDS Documents

Documents

Promotions

Promotions

RUO – Research Use Only