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4-Aminobutyric acid, 99+%

4-Aminobutyric acid, 99+%, CAS # 56-12-2, also known as γ-Aminobutyric acid, is an amino acid that shows inhibitory activities against neurotransmitters, including GABA. | CAS: 56-12-2 | C4H9NO2 | 103.12 g/mol

Supplier:  Thermo Scientific Chemicals 103281000

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Catalog No. AC103281000


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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 4-Aminobutyric acid is a γ-amino acid and monocarboxylic acid derived from butyric acid

• It is an amino acid that shows inhibitory activities against neurotransmitters, including GABA, and acts by binding GABA-A receptor and inhibiting the activity of signal-receiving neurons

• This compound, converted from neurotransmitter glutamate, is essential to regulate neuronal excitability

• It binds to GABA-A and GABA-B receptors, causing ion channel opening, hyperpolarization, and eventually inhibition of neurotransmission

Applications

• 4-Aminobutyric acid has been used in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for immunohistochemical experiments

• It is used, in vivo, to detect GABA neurotransmitter by magnetic resonance spectroscopy

• This compound increases the production of short-chain fatty acids and decreases pH values in mouse colon

• Some in vivo experiments, using rats, mice, and pigs, demonstrated that 4-Aminobutyric acid can modulate intestinal fluid secretion, blood flow and ulceration

Specifications

Specifications

197°C to 204°C
99+%
99.0
White
0.5% max.
C4H9NO2
H2N(CH2)3CO2H
04,413
15,425
Solubility in water: very soluble. Other solubilities: slightly soluble in common solvents
C(CC(=O)O)CN
103.12
119
103.12
Crystalline Powder
4-Aminobutyric acid
56-12-2
100.0
Authentic
99+%
Plastic Bottle
MFCD00008226
95% min. (c=10, 2N HCl, 430nm) 1cm cell
4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino
BTCSSZJGUNDROE-UHFFFAOYSA-N
4-aminobutanoic acid
100 g
CHEBI:16865
≥99%

Chemical Identifiers

56-12-2
103.12
BTCSSZJGUNDROE-UHFFFAOYSA-N
119
4-aminobutanoic acid
C4H9NO2
MFCD00008226
4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino
CHEBI:16865
C(CC(=O)O)CN
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EINECSNumber : 200-258-6

RTECSNumber : ES6300000

TSCA : TSCA

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