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3-Isobutyl-1-methylxanthine
CAS: 28822-58-4 | C10H14N4O2 | 222.25 g/mol
Supplier: Thermo Scientific Chemicals J64598MC
Description
3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Inhibits the growth of carcinoma cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction.
Specifications
| 3-Isobutyl-1-methylxanthine | |
| 200°C to 201°C | |
| MFCD00005584 | |
| 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine | |
| APIXJSLKIYYUKG-UHFFFAOYSA-N | |
| 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione | |
| 3758 | |
| 222.24 |
| 28822-58-4 | |
| C10H14N4O2 | |
| 100 mg | |
| Soluble in ethanol. | |
| CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O | |
| 222.25 | |
| CHEBI:43253 | |
| Solid |
Chemical Identifiers
| 28822-58-4 | |
| 222.25 | |
| APIXJSLKIYYUKG-UHFFFAOYSA-N | |
| 3758 | |
| 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione |
| C10H14N4O2 | |
| MFCD00005584 | |
| 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine | |
| CHEBI:43253 | |
| CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O |
Safety and Handling
GHS H Statement
H302
Harmful if swallowed.
P264b-P270-P301+P312-P330-P501c
H302
EINECSNumber : 249-259-3
RTECSNumber : ZD8500000
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only