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Thermo Scientific Chemicals 2',3'-Dideoxycytidine, 98+%
CAS: 7481-89-2 | C9H13N3O3 | 211.22 g/mol
Supplier: Thermo Scientific Chemicals L10619MF
Description
2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
| 2′,3′-Dideoxycytidine | |
| 216°C to 220°C | |
| C9H13N3O3 | |
| 50 mg | |
| zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one | |
| WREGKURFCTUGRC-KGQMAECUNA-N | |
| 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one | |
| 24066 | |
| 211.22 | |
| Solid |
| 7481-89-2 | |
| Glass bottle | |
| MFCD00012188 | |
| 654956 | |
| Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C). | |
| NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1 | |
| 211.22 | |
| CHEBI:10101 | |
| ≥98% |
Chemical Identifiers
| 7481-89-2 | |
| 211.22 | |
| WREGKURFCTUGRC-KGQMAECUNA-N | |
| 24066 | |
| NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1 |
| C9H13N3O3 | |
| MFCD00012188 | |
| zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one | |
| CHEBI:10101 |
Safety and Handling
P201-P202-P281-P308+P313-P501c
H351
RTECSNumber : HA3870000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only